Post-Doctoral Fellow - Nucleic Acid Chemistry
Ontario Tech University
- Oshawa, ON
- Permanent
- Full-time
- The candidate will synthesize phosphoramidites, and use solid-phase RNA synthesis to synthesize novel folatelabeled RNAs for gene silencing in kidney cells
- The candidate will HPLC purify oligonucleotides, and use mass spectrometry, circular dichroism, and UVmonitored thermal denaturation analysis to characterize the oligonucleotides
- PhD in Chemistry, Chemical Biology or a related field
- Experience with organic chemistry, phosphoramidite synthesis, and solid-phase oligonucleotide synthesis
- Experience with HPLC
- Understanding and experience with in vitro cell lines and PCR would be an asset