
Postdoctoral Fellow in Machine Learning for Multimodal Healthcare AI
- Toronto, ON
- Temporary
- Full-time
Number of Vacancies: 1
Site: Toronto General Hospital Research
Department: Multi organ Transplant
Reports to: Dr. Mamatha Bhat
Hours: 37.5
Shifts: Monday to Friday
Status: Temporary Full-Time
Closing Date: October 31, 2025Position SummaryWe're seeking a Postdoctoral Research Fellow in Machine Learning / Computer Science to help build the next frontier of deep learning, multimodal fusion, and longitudinal modeling in clinical medicine. This unique position offers the opportunity to work at the intersection of AI, healthcare, and translational science tackling some of the most complex challenges in transplant medicine and liver disease. The candidate would be co-supervised by both Dr. Mamatha Bhat (clinician), and Dr. Divya Sharma (Computer Science).
- Build generative and predictive models using longitudinal, multimodal patient data including clinical variables, labs, imaging, pathology, and multi-omics.
- Design and deploy foundation model-inspired architectures for real-time clinical applications.
- Incorporate causal inference and counterfactual modeling to guide treatment simulations and improve decision-making.
- Develop clinician-facing software tools that embed your ML models into UHN's digital ecosystem.
- Contribute to high-impact research publications, funding proposals, and collaborative innovations across AI and medicine.
- innovations across AI and medicine.
- Preprocess and harmonize large-scale longitudinal datasets comprising structured (clinical/lab) and unstructured (imaging, pathology, molecular) data.
- Develop reproducible pipelines for multimodal data ingestion from diverse health system and research sources (e.g., EHRs, biobanks, imaging repositories).
- Design, train, and validate predictive and generative models leveraging deep learning, causal inference, and time-aware architectures.
- Build foundation model-inspired pipelines for patient trajectory modeling, treatment response simulation, and risk stratification in liver disease and transplantation.
- Translate research outputs into clinician-facing software applications, ensuring integration into UHN's digital ecosystem.
- Build user-friendly, interpretable tools with real-time capability to support decision-making in complex clinical workflows.
- Co-lead hypothesis-driven, translational research in collaboration with clinicians, data scientists, and health system partners.
- Explore novel computational strategies for multimodal fusion and disease modeling.
- Contribute to high-impact publications, presentations, and grant proposals that bridge AI and healthcare.
- Document technical workflows and model development for reproducibility and knowledge sharing.
- Engage with and support junior trainees, including students and analysts, contributing to shared project goals and team culture.
- Collaborate closely with supervisors Dr. Mamatha Bhat and Dr. Divya Sharma through regular joint meetings and milestone planning.
- Stay current on state-of-the-art developments in machine learning, generative modeling, and precision medicine.
- Adapt models and methods to evolving project requirements in a fast-paced, interdisciplinary environment.
- A recent (or soon-to-be) PhD graduate in Machine Learning, Computer Science, Bioinformatics, or related fields.
- Fluent in Python, and experienced with deep learning frameworks like PyTorch or TensorFlow.
- Familiar with (or excited to learn) deep generative models, causal ML, transformer architectures, foundational models and multimodal learning.
- A collaborative and curious researcher with a strong publication record, excellent communication skills, and a passion for translational AI in medicine.
- Competitive offer packages
- Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP
- A flexible work environment
- Opportunities for development and promotions within a large organization
- Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)